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Doctor Daniel Pine estimates that approximately 30-50% of the risk for anxiety and depression is genetic. Genetic treatments are an exciting area of research currently.

Doctor Daniel Pine introduces the diathesis-stress model for anxiety and depression. The model posits that stress combines with inherited factors to produce disorder.

Doctor Daniel Pine explains that the amygdala is involved in learning to respond to a fearful experience fear-learning. There is evidence that the same response can lead to PTSD.

Doctor Daniel Pine introduces the fight-or-flight response, which is a common mechanism in mammals in response to a threat. It prepares the body to either run away or fight the threat.

Doctor Daniel Pine discusses explains that anxiety is more common in girls and women. Depression is also more common in women, but only after puberty. Anxiety may predict depression.

Doctor Daniel Pine makes the important point that the idea of a ‘chemical imbalance’ as a cause of disorders has pretty much rightfully been given up.

Doctor Daniel Pine defines anxiety as fear and apprehension about dangers that are not immediately present. Over time, anxiety can lead to depression.